Assignment Task
Task
Vilazodone Drug – Write a report on its target, how it was discovered and finally scaled-up to make multi kilo quantities.
Include the following in the report:
1. Target Section: This section should include the mechanism of action, the target of the drug, details about the disease area. Provide an illustration to support the discussion.
2. Discovery Section: This section should describe how the drug was discovered and details about structure activity relationship studies. Provide illustrations to support your discussion. Then discuss how the drug was synthesized during discovery phase – provide a scheme of the synthesis. (Refer to Lecture 4)
3. Process Development Section: This section should describe how the drug was scaled-up to make multi kilo quantities. Provide a scheme of the process. (Refer to Lecture 5/6).
4. Please pay attention to all the requirements of the assignment. Provide illustrations, schemes and structures where requested. Pay attention that the structures are visible and synthetic conditions are described properly.
5. If the scale-up route or structure activity relationship studies are not available then don’t pick that drug for the assignment. The selection of an appropriate drug that provides all the information required is part of the grade.
6. Provide all references at the end of the assignment. Provide the original reference articles separately.
7. Stick to a 6 page limit.
Tips for searching for a drug: Pick a drug that is in the market (can be a generic). Then find the chemical name of that drug – which will be readily available on google. After you know the chemical name you can search for the discovery route, structure activity relationship studies, target of mechanism and process scale-up route using that chemical name. Please provide the references you get all this information from.There can be multiple scale-up routes. It is okay – you just need to pick one. Discovery routes are done on small milligram scale. Process scale-up routes will be done on multi-gram, then multi-kilo and then multi ton scale. Every time the route could change. You don’t have to provide all scale-up routes. Just one is fine. It also doesn’t have to be the route used for commercial manufacturing either. It could be a scale-up route that was used for Phase 1 or 2 or 3 clinical studies.
This assignment is not asking for the formulation or drug product details so please do not provide that.This assignment must be typed and submitted electronically in MS Word (.docx or .pdf) format. T
- Drug Selection Does not meet expectations (0) Meets some expectations (2) Meets all expectations (4) 4
- Target Discussion Does not meet expectations (0) Meets some expectations (2) Meets all expectations (4) 4
- Target Disease Area Does not meet expectations (0) Meets some expectations (2.5) Meets all expectations (5) 5
- Target Mechanism of action Does not meet expectations (0) Meets some expectations (2.5) Meets all expectations (5) 5
- Discovery Discussion Does not meet expectations (0) Meets some expectations (2.5) Meets all expectations (5) 5
- Structure activity R-ship Studies Does not meet expectations (0) Meets some expectations (2.5) Meets all expectations (5) 5
- Discovery Synthesis Does not meet expectations (0) Meets some expectations (2) Meets all expectations (4) 4
- Process Scale-up Discussion Does not meet expectations (0) Meets some expectations (3.5) Meets all expectations (7) 7
- Process Scale-up route Does not meet expectations (0) Meets some expectations (3.5) Meets all expectations (7) 7
- Format, language, adherence to requirements Does not meet expectations (0) Meets some expectations (2) Meets all expectations (4)
Welcome to our Online Essay Writing Agency. Securing higher grades costing your pocket? Order your assignment online at the lowest price now! Our online essay writers are able to provide high-quality assignment help within your deadline. With our homework writing company, you can order essays, term papers, research papers, capstone projects, movie review, presentation, annotated bibliography, reaction paper, research proposal, discussion, or another assignment without having to worry about its originality – we offer 100% original content written completely from scratch
A-Plus Writing Help For University Students
Get expert assistance in any academic field. All courses and programs covered.
Get Help Now!We write papers within your selected deadline. Just share the instructions
